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Chih-Yung Tang Selected Research

Myotonia Congenita (Thomsen Disease)

1/2020Defective Gating and Proteostasis of Human ClC-1 Chloride Channel: Molecular Pathophysiology of Myotonia Congenita.
11/2018FKBP8 Enhances Protein Stability of the CLC-1 Chloride Channel at the Plasma Membrane.
1/2016Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β.
1/2013Myotonia congenita mutation enhances the degradation of human CLC-1 chloride channels.
12/2012Dominantly inherited myotonia congenita resulting from a mutation that increases open probability of the muscle chloride channel CLC-1.

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Chih-Yung Tang Research Topics

Disease

5Myotonia Congenita (Thomsen Disease)
01/2020 - 12/2012
3Cerebellar Diseases (Cerebellar Syndrome)
07/2021 - 04/2006
3Type 2 Episodic Ataxia
01/2017 - 04/2006
2Ataxia (Dyssynergia)
01/2021 - 01/2017
2Myotonia
01/2020 - 01/2011
1Cerebellar Ataxia (Dysmetria)
07/2021
1Parkinsonian Disorders (Parkinsonism)
07/2021
1Cognitive Dysfunction
07/2021
1Ischemia
01/2021
1Hyperaldosteronism (Conn Syndrome)
01/2020
1Inborn Genetic Diseases (Disease, Hereditary)
11/2018
1Episodic Ataxia
01/2017
1Infections
01/2017
1Type 1 Episodic Ataxia
01/2016
1Muscular Diseases (Myopathy)
01/2013
1Muscular Dystrophies (Muscular Dystrophy)
12/2012
1Blister (Bulla)
03/2012
1Neoplasms (Cancer)
11/2009
1Nervous System Diseases (Neurological Disorders)
02/2008

Drug/Important Bio-Agent (IBA)

6Chloride Channels (Chloride Channel)IBA
01/2020 - 01/2011
4Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2011
3voltage-dependent calcium channel (P-Q type)IBA
01/2017 - 04/2006
2Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
01/2020 - 01/2017
2CalciumIBA
03/2012 - 02/2008
1IronIBA
07/2021
1Conditioned Culture MediaIBA
01/2021
1Oxygen (Dioxygen)IBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2021
1CLC-1 channelIBA
01/2020
1CLC-2 Chloride ChannelsIBA
01/2020
1Ligases (Synthetase)IBA
01/2017
1Small Interfering RNA (siRNA)IBA
01/2017
1UbiquitinIBA
01/2017
1Q-Type Calcium Channels (Q-Type Calcium Channel)IBA
01/2017
1Potassium Channels (Potassium Channel)IBA
01/2016
1ChloridesIBA
01/2013
1DNA (Deoxyribonucleic Acid)IBA
12/2012
1sodium-calcium exchanger 1IBA
03/2012
1Membrane Proteins (Integral Membrane Proteins)IBA
03/2012
1Protons (Proton)IBA
03/2012
1SodiumIBA
03/2012
1AntigensIBA
11/2009
1Interleukin-2 (IL2)IBA
11/2009